Medical science, drawn into focus.

Urinary Tract Infection

Overview Infection of the urinary tract is common and more so in women (due to shorter urethra and hormonal changes). UTIs may be classified as either a lower (Cystitis, urethritis and Prostatitis) or upper UTI (pyelonephritis). The main causative agents are bacteria such as E-coli. A lower UTI can progress to an upper UTI causing systemic symptoms…

Acute Kidney Injury (AKI)

Overview Acute kidney injury (AKI) (formerly acute renal failure) is the syndrome arising from a rapid fall in GFR (over hours to days). It is characterized by retention of both nitrogenous (including Urea and Creatinine) and non-nitrogenous waste products of metabolism, as well as disordered electrolyte, acid– base, and fluid homeostasis. AKI is neither a…

Generalised Anxiety Disorder

DSM V categorise these as seperate disorders Depressive disorders Bipolar disorders Anxiety disorders Anxiety Disorders Generalised Anxiety Disorder Specific Phobia Agoraphobia Social Anxiety Disorder Panic Disorder This will mainly focus on Generalised Anxiety Disorder and touches on Panic Disorder . Overview Generalized anxiety disorder (GAD) can be defined as anxiety and worry about several events…

Hyper-IgE Syndrome (Job’s Syndrome)

Overview Hyper-IgE syndrome (HIES) is a rare primary immunodeficiency characterised by markedly elevated serum IgE, recurrent staphylococcal skin and lung infections, eczema, and connective tissue/ skeletal abnormalities. Most commonly caused by autosomal dominant mutations in STAT3 , it results in impaired Th17 cell differentiation and defective neutrophil chemotaxis. Autosomal recessive forms (DOCK8, TYK2 mutations) present…

Inguinal Hernia

Overview Higher incidence among men 40 to 59 years of age. Although there are many different types of hernias, they are usually related to the abdomen, with approximately 75% of all hernias occurring in the inguinal region. Hernia contains omentum (90% of cases) or intestine (10% of cases). Inguinal hernias are at risk of irreducibility or incarceration, which…

Lymphoma

Types of Lymphoma Lymphoma is malignancy originating in the lymph nodes. There are two types: Hodgkins lymphoma Non-hodgkins lymphoma Classic Clinical Presentation  Lymphadenopathy Constitutional symptoms Fever Night sweats Weight loss Differential Diagnosis of Lymphadenopathy Lymphoma Leukaemia Metastasis Infection Connective tissue disease – rheumatoid arthritis, SLE Infiltration – sarcoidosis Drugs – phenytoin Hodgkin's lymphoma Non-Hodgkin's lymphoma…

Long-Term Complications of Diabetes (Overview)

Overview Classification Microvascular Complications Retinopathy Nephropathy Neuropathy Macrovascular Complications Coronary heart disease Cerebrovascular disease Diabetic foot Diabetic Retinopathy Overview Diabetes is the most common cause of blindness in the working population. Blindness is preventable. Annual retinal screening is advised for patients at risk. Pre-symptomatic screening enables laser photocoagulation to be used, aimed to stop production of…

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