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Haematology
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Lymphoma
Types of Lymphoma
Lymphoma is malignancy originating in the lymph nodes. There are two types:
Classic Clinical Presentation
- Lymphadenopathy
- Constitutional symptoms
- Fever
- Night sweats
- Weight loss
Differential Diagnosis of Lymphadenopathy
- Lymphoma
- Leukaemia
- Metastasis
- Infection
- Connective tissue disease - rheumatoid arthritis, SLE
- Infiltration - sarcoidosis
- Drugs - phenytoin
Hodgkin's lymphoma | Non-Hodgkin's lymphoma | |
Bimodal Distribution | ||
Risk Factors | EBV | EBV may be associated with HIV |
Lymph Nodes | Contiguous and localized | Noncontiguous and peripheral |
Histology | Reed-Sternberg cells | Majority involve B cells |
Treatment | ABVD | R-CHOP |