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Archives: Diseases

COPD

Overview The diagnosis of COPD is usually limited to individuals who have chronic airflow obstruction associated with tobacco smoke or some other noxious inhalant, and it is usually not difficult…
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Endometriosis

A healthy 25-year-old woman presents with worsening dysmenorrhea, pain of recent onset in the left lower quadrant, and dyspareunia. She has regular menstrual cycles, and her last menstrual period was…
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Coeliac Disease

Overview Coeliac disease is a systemic autoimmune disease triggered (T-lymphocytes) by dietary gluten peptides found in wheat, rye, barley, and related grains. Immune activation in the small intestine leads to villous…
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Inflammatory Bowel Disease

Overview  Inflammatory bowel disease is a common condition. It is divided into two types: Crohn disease and Ulcerative colitis. Both these condition differ in pathology, progression and complication, but they do…
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Graves’ Disease

Overview Graves’ disease is the most common cause of hyperthyroidism, caused by an autoimmune reaction in which TSH receptor autoantibodies stimulate the thyroid gland, leading to an increase in the…
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Diabetes Mellitus Type II

Overview Diabetes Mellitus type II is a progressive disorder defined by deficits in insulin secretion and action (insulin resistance). 1 in 12 people have diabetes (50% do not know they…
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Addison’s Disease

Overview Addison’s disease is a disease characterised by adrenal insufficiency. Adrenal insufficiency results in a decrease of the adrenal gland hormones: mineralocorticoids, glucocorticoids and to an extent androgens. There are…
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Cushing’s Disease

Overview Cushing’s disease is a ACTH dependent syndrome characterised by excess corticosteroid production from the adrenal glands. It is ACTH dependent because it is triggered by an ACTH-secreting pituitary tumour.…
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Multiple Sclerosis

“Each patient ought to feel somewhat the better after the physician’s visit irrespective of the nature of the illness.” -Warfield Theobald Longcope Overview Multiple sclerosis (MS) is defined as an…
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Parkinson’s Disease

Overview Parkinson’s disease is a progressive neurodegenerative disorder characterised by tremor, rigidity, bradykinesia, and a wide spectrum of non-motor symptoms including sleep disorders, hyposmia, bladder and bowel dysfunction, fatigue, dementia,…
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