pancreatitis

Pancreatitis is inflammation of the pancreas caused by premature activation of digestive enzymes within the gland, leading to autodigestion and tissue injury. It is clinically significant due to its potential to cause severe abdominal pain, systemic inflammatory response, and organ failure. Gallstones are a common cause, and a major complication is the development of pancreatic necrosis, which can result in infection and sepsis.