Overview Cushing’s disease is a ACTH dependent syndrome characterised by excess corticosteroid production from the adrenal glands. It is ACTH dependent because it is triggered by an ACTH-secreting pituitary…

Overview The muscle groups of the human limbs are divided into section or compartments. Acute compartment syndrome (ACS) occurs when increased pressure within a compartment compromises circulation and function…

Authors Overview Liver cysts are fluid filled cavities in the liver that are asymptomatic and usually found incidentally on abdominal imaging. Larger cysts are more commonly associated with symptoms…

Overview Higher incidence among men 40 to 59 years of age. Although there are many different types of hernias, they are usually related to the abdomen, with approximately 75% of all hernias occurring in…

Overview Diverticula of the colon consist of outpouchings of mucous membrane through the muscle wall of the bowel. In the colon, diverticula are found most commonly in the sigmoid and descending colon, and…

Overview Peptic ulcer refers to an ulcer in the lower oesophagus, stomach or duodenum. Incidence ↑ with age; both sexes are similarly affected. In the developed world, Helicobacter pylori incidence has been…

Overview Acute pancreatitis is a relatively common condition presenting with severe, acute, constant epigastric pain. Incidence of ~5 per 100,000/year. Acute pancreatitis has a significant mortality.…

Overview Acute kidney injury (AKI) (formerly acute renal failure) is the syndrome arising from a rapid fall in GFR (over hours to days). It is characterized by retention of both nitrogenous (including Urea…

Overview Third most common cause of death worldwide and most common cause of neurological disability. It is subdivided into ischaemic stroke (caused by vascular occlusion or stenosis) and haemorrhagic stroke…

Overview Cardiac arrest is a state of circulatory failure due to a loss of cardiac systolic function. It is the result of 4 specific cardiac rhythm disturbances: Epidemiology Initial Assessment and…