Arthritis

» Rheumatology

Overview Once arthritis is suspected, physicians should distinguish between noninflammatory and inflammatory forms of arthritis while recognizing potentially disabling and life-threatening problems.

Remember Rule out septic arthritis in any monoarthritic presentation, prolonged diagnosis results in irreversible joint damage

Definition
Polyarthralgia: multiple joint pain without synovities
Polyarthritis: inflammation of 4 or more joints (synovitis)

Monoarthropathy	Oligoarthropathy	Polyarthropathy
Septic arthritis	Crystal arthritis	Rheumatoid arthritis
Crystal arthritis (Gout)	Psoriatic arthritis	Viral Arthritis
Osteoarthritis (can be mono-poly)	Reactive arthritis	Autoimmune connective tissue disease (ie. SLE)
Trauma (Haemarthrosis)	Ankylosing spondylititis	Vasculitides (ie. Polymyalgia Rheumatica)

Approach

History
- Sex
- Age of onset
- Pattern of arthritis
- Extra-articular features
- Which joints affected
  - peripheral symmetrical arthritis - Rheumatoid arthritis
  - Asymmetric with enthesitis and back pain - spondylarthritis
  - DIP joints with synovitis - psoriatic arthritis

Age
Child	Trauma, Congenital, slipped capital femoral epihpysis, Juvenile rheumatoid arthritis
Young Adults	Reactive arthritis, gonococcal, SLE
Older patients	Acute gout and Pseudogout, Rheumatoid arthrits

Examination
- Psoraiasis
- Malar rash - SLE
- Kerataderma blenorrhagica - Septic arthritis
- Salmon
Investigations

Differential Diagnosis

Arthritis can be divided into:

Acute or chronic
Monoarthritis, Oligoarthritis, Polyarthritis
Inflammatory and non-inflammatory
Seropositive or seronegative

Non-inflammatory Arthritis

Inflammatory Arthritis

Crystal arthropathy
Infectious
Seronegative arthritis
- Ankylosing spondylitis
- Psoriatic arthritis
- Reactive arthritis
- IBD arthritis
Seropositive arthritis
- Rheumatoid Arthritis
- Scleroderma
- Vasculitis
- Sjogren's

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Differential Diagnosis

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Arthritis

Differential Diagnosis

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