Medical science, drawn into focus.

Sexual Transmitted Infection

Overview Sexually transmitted infections (STI) are a significant public health worldwide. STI can result in chronic disease, pregnancy complications, infertility, and even death. Globally, congenital syphilis is still a leading cause of stillbirth and neonatal death. Antibiotic-resistant Neisseria gonorrhoeae continues to be a significant public health concern.  Chlamydia trachomatis infection is the most frequently reported…

Hypermobility Syndromes

Overview Hypermobility Spectrum Disorder (HSD) describes symptomatic joint hypermobility with musculoskeletal (and sometimes systemic) consequences in people who do not meet the 2017 diagnostic criteria for hypermobile Ehlers–Danlos syndrome (hEDS) or another heritable connective-tissue disorder (HCTD). Prevalence of generalised joint hypermobility varies (≈2–35% depending on age/sex/ethnicity and cut-offs), with symptomatic states more common in females…

Pulmonary Sarcoidosis

Overview Sarcoidosis is a multisystem granulomatous disease of unknown cause, characterised by the formation of non‑caseating granulomas in affected organs. Pulmonary involvement occurs in ~90% of patients, making it the most common manifestation. Global prevalence varies widely (e.g., 3.7/100,000 in Japan vs. 28.2/100,000 in Finland), with higher rates in Black Americans and Northern Europeans. Peak…

Endometrial Cancer

Overview Endometrial carcinoma is an epithelial malignancy of the uterine corpus mucosa, usually an adenocarcinoma. Endometrial carcinoma is the most common female genital tract malignancy. Postmenopausal bleeding always needs to be investigated because it can indicate malignant disorders and premalignant conditions, such as endometrial hyperplasia. The most common etiology of postmenopausal bleeding is atrophic endometritis or vaginitis. Menopause:…

Acute Respiratory Failure

Overview  Acute Respiratory failure causes hypoxia and/or impaired ventilation with hypercapnia, leading to severe hypoxemia and rapid deterioration. Two main types of respiratory failure: Type I respiratory failure (non-hypercapniec respiratory failure) Primarily from failure of oxygenation (PaO2 <60mmHg) Normal or low CO2 pH 7.5 Usually responds to Oxygen therapy Type II respiratory failure (hypercapniec respiratory…

Multiple Sclerosis

"Each patient ought to feel somewhat the better after the physician's visit irrespective of the nature of the illness." -Warfield Theobald Longcope Overview Multiple sclerosis (MS) is defined as an inflammatory demyelinating disease characterised by the presence of episodic neurological dysfunction in at least 2 areas of the CNS (brain, spinal cord, and optic nerves)…

Prostatitis

Overview Prostatitis refers to a spectrum of conditions involving inflammation of the prostate gland, ranging from acute bacterial infection to chronic pelvic pain syndromes. It is a common urological condition affecting men of all ages, particularly those aged 30–50 years. The National Institutes of Health (NIH) classifies prostatitis into four categories: acute bacterial, chronic bacterial, chronic…

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