Medical science, drawn into focus.

Deep Vein Thrombosis

Overview Deep vein thrombosis (DVT) is the formation of a blood clot in a vein deep under the skin 25-50% of surgical patients and many non-surgical patients. 65% of DVT are below the knee are symptomatic and rarely embolism to the lung. There are many causes of DVT. Thrombus:  blood clot  Thrombosis:  blood clot that forms in…

Psoriatic Arthritis

Overview Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory arthritis associated with psoriasis, affecting up to 30% of patients with skin psoriasis. It commonly presents in adults aged 30–50 years, with equal gender distribution. The disease is highly variable, involving peripheral joints, axial skeleton, entheses, and skin/nails. Delay in diagnosis is common and can result…

Hodgkins Lymphoma

Overview Hodgkin lymphoma (HL) arises from germinal center or post-germinal center B cells. HL has a unique cellular composition, containing a minority of neoplastic cells ( Reed-Sternberg cells  and their variants) in an inflammatory background. Reed-Sternberg cell is a characteristic feature of HL. Epidemiology Lymphoma is divided into Hodgkins and Non-Hodgkins Hodgkins lymphoma accounts for…

Parkinson's Disease

Overview Parkinson’s disease is a progressive neurodegenerative disorder characterised by tremor, rigidity, bradykinesia, and a wide spectrum of non-motor symptoms including sleep disorders, hyposmia, bladder and bowel dysfunction, fatigue, dementia, and other neuropsychiatric symptom. Although the disease has no cure, available treatments effectively control motor symptoms and improve quality of life. Parkinson disease affects approximately 1…

Umbilical Hernia

Overview Umbilical hernias are one of the most common surgical conditions in infants and children. In infantile umbilical hernia there is a pathological failure of obliteration of umbilical defect. Umbilical hernia can also occur in adults and is usually acquired due to increased intrabdominal pressure due to obesity, pregnancy, ascites. Management is surgery. Hernia:  A bulge or protrusion of…

Reactive Arthritis

Overview Reactive arthritis is a seronegative spondyloarthropathy that occurs after a genitourinary or gastrointestinal infection, typically presenting as an asymmetric oligoarthritis, often with associated conjunctivitis and urethritis (formerly Reiter’s syndrome). It most commonly affects young adults aged 20–40 and shows a strong association with HLA-B27. Incidence is estimated at 30–40 per 100,000, with higher rates…

Pneumonia

Overview Pneumonia is infection in the lower respiratory tract and is characterised by fevers, purulent sputum, leucocytosis, low oxygen levels and new lung infiltrates (consolidation) on radiographic imaging. The infection is identified by the site of consolidation. Consolidation is where the lung tissue is filled with fluid (ie. water, blood, pus, microbes). Types of pneumonia…

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