Overview Sjögren’s Syndrome is a chronic, systemic autoimmune disorder characterized by lymphocytic infiltration and destruction of exocrine glands, primarily affecting the salivary and lacrimal glands, leading…

Overview Shoulder impingement syndrome, now more commonly referred to as subacromial pain syndrome (SAPS), is one of the most frequent causes of shoulder pain. It accounts for ~40–65% of shoulder complaints in…

Overview Reactive arthritis is a seronegative spondyloarthropathy that occurs after a genitourinary or gastrointestinal infection, typically presenting as an asymmetric oligoarthritis, often with…

Overview Psoriatic arthritis (PsA) is a chronic, immune-mediated inflammatory arthritis associated with psoriasis, affecting up to 30% of patients with skin psoriasis. It commonly presents in adults aged 30–50…

Overview Pseudogout, more accurately known as calcium pyrophosphate deposition disease (CPPD), is a crystal arthropathy characterized by the deposition of calcium pyrophosphate dihydrate crystals in…

Overview Hypothyroidism is a clinical state resulting from underproduction of the thyroid hormones T4 and T3. Most cases (95%) are due to primary hypothyroidism, a failure of the thyroid gland to produce…

Overview Pericarditis is the most common form of pericardial disease and a relatively common cause of chest pain. The etiology of pericarditis may be infectious (eg, viral and bacterial) or noninfectious…

Overview Myasthenia Gravis (MG) is a chronic autoimmune neuromuscular disorder where antibodies target acetylcholine receptors (AChR) or MuSK proteins at the post-synaptic membrane, impairing…

Overview MCTD is a systemic autoimmune rheumatic disease characterized by overlapping clinical features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc), polymyositis, with rheumatoid arthritis…

Overview Basic Calcium Phosphate (BCP) disease is a crystal-associated arthropathy characterized by deposition of BCP crystals in periarticular and intra-articular tissues. A severe clinical presentation of…