Notes »
disease
Thyroid Tumours
Overview
Classification
Papillary thyroid carcinoma constitutes approximately 80% of all thyroid cancers. It is more common in women.
Follicular thyroid carcinoma constitutes 15% of all thyroid cancers. The mean patient age in most studies is 50 years. FTC is more common in women
Medullary thyroid carcinoma (MTC) is associated with MEN type 2. MTC accounts for 5–10% of all thyroid cancers. Presents with a lump in the neck and calcitonin systemic effects include flushing and diarrhea
Anaplastic (undifferentiated) thyroid cancer is rare with a peak incidence in the seventh decade. It is characterized by rapid growth of a firm/hard fixed tumor.
Lymphoma is uncommon. Almost always associated with autoimmune thyroid disease (Hashimoto’s thyroiditis). Occurs more commonly in women and in patients aged >40 years. It is Characterized by rapid enlargement of the thyroid gland
Signs and Symptoms
Aetiology
- Irradiation
- Iodine - follicular carcinoma
- Genetic syndrome (RET/PTC1, RET/PTC2 and RET/PTC3 TRK (less common)
- Papillary microcarcinoma of the thyroid (PMC)
Pathophysiology
Management
Remember Thyroglobulin is the marker to measure thyroid cancer function post treatment |