Chronic kidney disease (CKD) is a progressive loss of kidney function over three months or more, characterised by a decrease in glomerular filtration rate (GFR) or evidence of kidney damage. It is clinically significant as it increases the risk of cardiovascular disease, necessitates careful management of comorbidities, and can lead to end-stage renal failure requiring dialysis or transplantation. A common complication of CKD is hyperkalemia, which can cause life-threatening cardiac arrhythmias.
