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Lymphoma

Types of Lymphoma

Lymphoma is malignancy originating in the lymph nodes. There are two types:

Classic Clinical Presentation 

  • Lymphadenopathy
  • Constitutional symptoms
    • Fever
    • Night sweats
    • Weight loss

Differential Diagnosis of Lymphadenopathy

  • Lymphoma
  • Leukaemia
  • Metastasis
  • Infection
  • Connective tissue disease – rheumatoid arthritis, SLE
  • Infiltration – sarcoidosis
  • Drugs – phenytoin
Hodgkin’s lymphomaNon-Hodgkin’s lymphoma
Bimodal Distribution
Risk FactorsEBVEBV may be associated with HIV
Lymph NodesContiguous and localizedNoncontiguous and peripheral
HistologyReed-Sternberg cellsMajority involve B cells
TreatmentABVDR-CHOP

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