Armando Hasudungan
Biology and Medicine videos

Jaundice

Overview Jaundice or icterus is the yellowish discoloration of the skin and sclerae from increased levels of bilirubin, a bile pigment derived chiefly from the breakdown of hemoglobin. Mechanism of Jaundice Increased production of bilirubin Decrease uptake of bilirubin by the hepatocytes Decreased ability of the liver to conjugate bilirubin Decreased excretion of bilirubin into the […]

Overview Jaundice or icterus is the yellowish discoloration of the skin and sclerae from increased levels of bilirubin, a bile pigment derived chiefly from the breakdown of hemoglobin.

Mechanism of Jaundice

  • Increased production of bilirubin
  • Decrease uptake of bilirubin by the hepatocytes
  • Decreased ability of the liver to conjugate bilirubin
  • Decreased excretion of bilirubin into the bile, resulting in absorption of conjugated bilirubin back into the blood

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